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Padres host the Guardians on 6-game home win streak

Cleveland Guardians (2-3) vs. San Diego Padres (6-0) San Diego; Wednesday, 4:10 p.m. EDT PITCHING PROBABLES: Guardians: Ben Lively (0-0, 5.40 ERA, 0.80 WHIP, three strikeouts); Padres: Dylan Cease (0-0, 6.23 ERA, 1.

O'Neill leads Orioles against the Red Sox after 4-hit outing

Boston Red Sox (1-4) vs. Baltimore Orioles (3-2) Baltimore; Wednesday, 6:35 p.m. EDT PITCHING PROBABLES: Red Sox: Garrett Crochet (0-0, 3.60 ERA, 1.40 WHIP, four strikeouts); Orioles: Zach Eflin (1-0, 3.00 ERA, 0.

Marlins play the Mets in series rubber match

New York Mets (2-3) vs. Miami Marlins (4-2) Miami; Wednesday, 4:40 p.m. EDT PITCHING PROBABLES: Mets: Clay Holmes (0-1, 3.86 ERA, 1.93 WHIP, four strikeouts); Marlins: Connor Gillispie (0-1, 5.40 ERA, 1.

Rays play the Pirates on home winning streak

Pittsburgh Pirates (1-5) vs. Tampa Bay Rays (4-1) Tampa, Florida; Wednesday, 1:10 p.m. EDT PITCHING PROBABLES: Pirates: Paul Skenes (0-0, 3.38 ERA, 0.94 WHIP, seven strikeouts); Rays: Ryan Pepiot (0-0, 1.50 ERA, 1.

Reds and Rangers square off with series tied 1-1

Texas Rangers (4-2) vs. Cincinnati Reds (2-3) Cincinnati; Wednesday, 12:40 p.m. EDT PITCHING PROBABLES: Rangers: Jack Leiter (1-0, 1.80 ERA, 1.20 WHIP, four strikeouts); Reds: Hunter Greene (0-0, 3.60 ERA, 0.

Dodgers look to keep home win streak going, host the Braves

Atlanta Braves (0-6) vs. Los Angeles Dodgers (7-0) Los Angeles; Wednesday, 8:38 p.m. EDT PITCHING PROBABLES: Braves: Bryce Elder (0-0); Dodgers: Blake Snell (1-0, 3.60 ERA, 1.

Athletics aim to break losing streak in game against the Cubs

Chicago Cubs (4-4) vs. Athletics (2-4) West Sacramento, California; Wednesday, 3:35 p.m. EDT PITCHING PROBABLES: Cubs: Jameson Taillon (0-1, 12.46 ERA, 2.08 WHIP, one strikeout); Athletics: Jeffrey Springs (1-0, 0.00 ERA, 0.

Angels visit the Cardinals on 4-game road win streak

Los Angeles Angels (4-1) vs. St. Louis Cardinals (3-2) St. Louis; Wednesday, 1:15 p.m. EDT PITCHING PROBABLES: Angels: Yusei Kikuchi (0-1, 4.50 ERA, 0.83 WHIP, five strikeouts); Cardinals: Sonny Gray (1-0, 3.60 ERA, 1.

Diamondbacks meet the Yankees with 1-0 series lead

Arizona Diamondbacks (3-2) vs. New York Yankees (3-1) New York; Wednesday, 7:05 p.m. EDT PITCHING PROBABLES: Diamondbacks: Zac Gallen (0-1, 9.00 ERA, 2.00 WHIP, four strikeouts); Yankees: Carlos Rodon (1-0, 1.69 ERA, 1.

White Sox and Twins play to determine series winner

Minnesota Twins (1-4) vs. Chicago White Sox (2-3) Chicago; Wednesday, 2:10 p.m. EDT PITCHING PROBABLES: Twins: Pablo Lopez (0-1, 3.60 ERA, 1.60 WHIP, three strikeouts); White Sox: Sean Burke (1-0, 0.00 ERA, 0.